/*
Theme Name: Oncopod.2v
Theme URI: https://www.oncopod.com/
Author: Oncopod
Description: Independent, Elementor-free WordPress theme for the existing Oncopod oncology information library. Preserves existing content and published URLs.
Version: 6.4.1
Requires at least: 6.0
Requires PHP: 7.4
Text Domain: oncopod
*/
:root{--op-navy:#173b50;--op-ink:#263944;--op-muted:#647681;--op-accent:#168f84;--op-accent-dark:#0f756c;--op-soft:#f5f8f8;--op-soft2:#eef4f4;--op-line:#d9e4e7;--op-white:#fff;--op-max:1180px;--op-radius:12px;--op-shadow:0 5px 20px rgba(23,59,80,.055)}
*{box-sizing:border-box}html{scroll-behavior:smooth}body{margin:0;background:#fff;color:var(--op-ink);font-family:Arial,Helvetica,sans-serif;line-height:1.7}img{max-width:100%;height:auto;display:block}a{color:var(--op-accent-dark);text-decoration:none}a:hover{color:var(--op-accent)}button,input,textarea,select{font:inherit}.container{width:min(calc(100% - 32px),var(--op-max));margin-inline:auto}.screen-reader-text{position:absolute!important;width:1px;height:1px;padding:0;margin:-1px;overflow:hidden;clip:rect(0,0,0,0);white-space:nowrap;border:0}
.site-header{position:sticky;top:0;z-index:1000;background:#fff;border-bottom:1px solid var(--op-line);box-shadow:0 2px 12px rgba(23,59,80,.035)}.admin-bar .site-header{top:32px}.header-main{min-height:78px;display:flex;align-items:center;gap:22px}.brand-logo{display:flex;align-items:center;flex:0 0 auto}.brand-logo img{width:190px;height:auto;max-height:58px}.header-search{flex:1;max-width:430px;margin-left:auto}.search-form{display:flex;border:1px solid var(--op-line);border-radius:999px;overflow:hidden;background:#fff}.search-form input{border:0;outline:0;padding:10px 15px;min-width:0;flex:1;color:var(--op-ink)}.search-form button{border:0;background:var(--op-accent);color:#fff;padding:0 17px;cursor:pointer}.header-actions{display:flex;align-items:center;gap:12px}.header-contact{display:inline-flex;align-items:center;justify-content:center;padding:10px 15px;border:0;border-radius:999px;background:var(--op-accent);color:#fff;font-weight:700;cursor:pointer}.header-contact:hover{background:var(--op-accent-dark)}.language{font-size:13px;color:var(--op-muted)}.menu-toggle{display:none;border:0;background:none;font-size:28px;color:var(--op-navy);cursor:pointer}.main-nav{background:var(--op-navy)}.main-menu{list-style:none;margin:0;padding:0;display:flex;flex-wrap:wrap}.main-menu li a{display:block;color:#fff;padding:10px 14px;font-size:13px;font-weight:700;white-space:nowrap}.main-menu li a:hover{background:rgba(255,255,255,.10);color:#fff}
.hero{background:#f6f9f9;border-bottom:1px solid var(--op-line);padding:72px 0}.hero-grid{display:grid;grid-template-columns:1.06fr .94fr;gap:52px;align-items:center}.eyebrow{text-transform:uppercase;letter-spacing:1.15px;font-size:11px;font-weight:800;color:var(--op-accent-dark)}.hero h1{font-size:clamp(38px,5vw,60px);line-height:1.05;letter-spacing:-2px;color:var(--op-navy);margin:10px 0 20px}.hero p{font-size:18px;color:var(--op-muted);max-width:680px}.hero-actions{display:flex;gap:10px;flex-wrap:wrap;margin-top:25px}.btn{display:inline-flex;align-items:center;justify-content:center;border-radius:999px;padding:11px 18px;font-weight:700;border:1px solid transparent;cursor:pointer}.btn-primary{background:var(--op-accent);color:#fff}.btn-primary:hover{background:var(--op-accent-dark);color:#fff}.btn-outline{background:#fff;border-color:var(--op-accent);color:var(--op-accent-dark)}.btn-outline:hover{background:var(--op-soft);color:var(--op-accent-dark)}.hero-reference{background:#fff;border:1px solid var(--op-line);border-radius:14px;padding:30px;box-shadow:var(--op-shadow)}.hero-reference-mark{width:50px;height:50px;border-radius:10px;background:var(--op-soft2);display:grid;place-items:center;color:var(--op-accent-dark);font-weight:800;margin-bottom:22px}.hero-reference h2{color:var(--op-navy);font-size:29px;line-height:1.2;margin:8px 0 10px}.hero-reference p{font-size:15px}.hero-reference-rule{border-top:1px solid var(--op-line);margin:25px 0 7px}.hero-reference-links a{display:flex;justify-content:space-between;padding:10px 0;border-bottom:1px solid var(--op-line);font-weight:700}.hero-reference-links a:last-child{border-bottom:0}
.section{padding:62px 0}.section-alt{background:var(--op-soft)}.section-head{display:flex;justify-content:space-between;align-items:end;gap:20px;margin-bottom:25px}.section-head h2{margin:4px 0 0;color:var(--op-navy);font-size:31px;letter-spacing:-.6px}.section-head p{margin:5px 0 0;color:var(--op-muted)}.card-grid{display:grid;grid-template-columns:repeat(3,1fr);gap:18px}.info-card{background:#fff;border:1px solid var(--op-line);border-radius:var(--op-radius);padding:24px;box-shadow:var(--op-shadow)}.feature-card{display:flex;flex-direction:column;min-height:205px}.feature-card span{margin-top:auto;padding-top:18px;font-size:13px;font-weight:800;color:var(--op-accent-dark)}.info-icon{width:46px;height:46px;border-radius:10px;background:#edf5f4;color:var(--op-accent-dark);display:grid;place-items:center;font-weight:800;margin-bottom:14px}.info-card h3{margin:0 0 7px;color:var(--op-navy);font-size:19px}.info-card p{margin:0;color:var(--op-muted)}.resource-grid{display:grid;grid-template-columns:repeat(3,1fr);border-top:1px solid var(--op-line);border-bottom:1px solid var(--op-line)}.resource-row{display:grid;grid-template-columns:44px 1fr 20px;gap:14px;align-items:center;padding:22px 18px;border-right:1px solid var(--op-line);color:var(--op-ink)}.resource-row:last-child{border-right:0}.resource-row:hover{background:#fff}.resource-row strong{display:block;color:var(--op-navy)}.resource-row small{display:block;color:var(--op-muted);font-size:13px;line-height:1.45;margin-top:3px}.resource-row b{color:var(--op-accent-dark)}.resource-icon{width:40px;height:40px;border-radius:9px;background:#fff;border:1px solid var(--op-line);display:grid;place-items:center;font-size:12px;font-weight:800;color:var(--op-accent-dark)}.cta{background:var(--op-navy);color:#fff;border-radius:14px;padding:38px;display:flex;justify-content:space-between;align-items:center;gap:24px}.cta h2{margin:5px 0 7px;font-size:30px}.cta p{margin:0;color:#d7e5e9;max-width:760px}.cta .btn{background:#fff;color:var(--op-navy)}.cta-eyebrow{color:#9fd3cd}
.content-wrap{padding:50px 0}.reference-layout{display:grid;grid-template-columns:minmax(0,1fr) 285px;gap:42px}.article{min-width:0}.article-header h1,.reference-hero h1{font-size:clamp(34px,4vw,52px);line-height:1.1;color:var(--op-navy);margin:6px 0 12px}.reference-hero{background:#f6f9f9;border-bottom:1px solid var(--op-line);padding:43px 0}.reference-hero p{color:var(--op-muted);font-size:17px;max-width:820px;margin:0}.breadcrumbs{font-size:12px;color:var(--op-muted);margin-bottom:16px}.breadcrumbs span{padding:0 6px;color:#a5b4ba}.reference-actions{display:flex;gap:9px;flex-wrap:wrap;margin-top:20px}.article-content{font-size:17px;min-width:0}.article-content h2,.article-content h3,.article-content h4{color:var(--op-navy);line-height:1.3;margin:34px 0 12px;scroll-margin-top:125px}.article-content p{margin:0 0 18px}.article-content ul,.article-content ol{padding-left:24px}.article-content li{margin:5px 0}.article-content table{width:100%;border-collapse:collapse;margin:25px 0;font-size:15px}.article-content th,.article-content td{border:1px solid var(--op-line);padding:10px 12px;text-align:left;vertical-align:top}.article-content th{background:var(--op-soft);color:var(--op-navy)}.article-content tr:nth-child(even) td{background:#fbfcfc}.article-content img{border-radius:8px}.article-content blockquote{margin:25px 0;padding:18px 22px;background:var(--op-soft);border-left:3px solid var(--op-accent)}.article-content a{text-decoration:underline;text-decoration-color:#b8d5d1;text-underline-offset:3px}.article-content a:hover{text-decoration-color:var(--op-accent)}.toc{position:sticky;top:110px;background:#fff;border:1px solid var(--op-line);border-radius:12px;padding:17px}.toc h3{margin:0 0 9px;color:var(--op-navy);font-size:16px}.toc ul{list-style:none;padding:0;margin:0}.toc li{margin:7px 0}.toc a{font-size:13px}.side-card{background:var(--op-soft);border:1px solid var(--op-line);border-radius:12px;padding:19px;margin-top:16px}.side-card h3{margin:0 0 7px;color:var(--op-navy)}.side-card p{font-size:14px;color:var(--op-muted);margin:0 0 14px}.reference-tabs{display:flex;gap:0;overflow:auto;border-bottom:1px solid var(--op-line);margin-bottom:28px}.reference-tabs a{white-space:nowrap;padding:11px 15px;border-bottom:2px solid transparent;font-size:14px;font-weight:700}.reference-tabs a:hover{border-color:var(--op-accent)}.source-panel{background:var(--op-soft);border:1px solid var(--op-line);border-radius:12px;padding:22px;margin-top:32px}.source-panel .source-kicker{font-size:11px;letter-spacing:1px;font-weight:800;color:var(--op-accent-dark)}.source-panel h2{font-size:21px;margin:5px 0;color:var(--op-navy)}.source-panel p{font-size:14px;color:var(--op-muted)}
.directory-toolbar{display:flex;gap:14px;align-items:center;margin:28px 0 15px;flex-wrap:wrap}.directory-search{flex:1;min-width:250px;border:1px solid var(--op-line);border-radius:999px;padding:13px 17px;outline:0;color:var(--op-ink);background:#fff}.directory-search:focus{border-color:#9bc7c2;box-shadow:0 0 0 3px rgba(22,143,132,.08)}.directory-count{font-size:12px;color:var(--op-muted);white-space:nowrap}.az-links{display:flex;gap:6px;flex-wrap:wrap;margin:14px 0 34px}.az-links a{width:35px;height:35px;border:1px solid var(--op-line);border-radius:8px;display:grid;place-items:center;font-weight:800;color:var(--op-accent-dark);font-size:13px}.az-links a:hover,.az-links a.active{background:var(--op-accent);border-color:var(--op-accent);color:#fff}.az-group{margin:32px 0}.az-heading{display:flex;align-items:center;gap:14px;margin-bottom:10px}.az-letter{font-size:25px;line-height:1;font-weight:800;color:var(--op-navy)}.az-rule{height:1px;background:var(--op-line);flex:1}.directory-list{display:grid;grid-template-columns:repeat(2,1fr);gap:8px}.directory-item{position:relative;display:block;background:#fff;border:1px solid var(--op-line);border-radius:9px;padding:14px 42px 14px 15px;color:var(--op-ink)}.directory-item:hover{border-color:#a9cfca;box-shadow:var(--op-shadow)}.directory-title{display:block;color:var(--op-navy);font-weight:800}.directory-excerpt{display:block;font-size:12px;line-height:1.5;color:var(--op-muted);margin-top:3px}.directory-arrow{position:absolute;right:14px;top:50%;transform:translateY(-50%);color:var(--op-accent-dark);font-weight:800}.directory-empty{display:none;padding:20px;background:var(--op-soft);border:1px solid var(--op-line);border-radius:9px;color:var(--op-muted)}
.search-hero-form{max-width:700px;margin-top:22px}.search-hero-form .search-form{background:#fff}.search-results-head{font-size:13px;color:var(--op-muted);margin-bottom:15px}.search-list{max-width:900px}.search-result{padding:24px 0;border-top:1px solid var(--op-line)}.search-result:last-child{border-bottom:1px solid var(--op-line)}.search-result .result-type{font-size:10px;letter-spacing:1px;text-transform:uppercase;font-weight:800;color:var(--op-accent-dark)}.search-result h2{font-size:24px;line-height:1.25;margin:5px 0}.search-result h2 a{color:var(--op-navy)}.search-result p{margin:0 0 8px;color:var(--op-muted)}.result-link{font-size:13px;font-weight:800}.empty-state{padding:40px 0}.empty-state h2{color:var(--op-navy)}
.footer{background:#123246;color:#cbdce2;margin-top:50px}.footer-main{padding:46px 0 30px}.footer-grid{display:grid;grid-template-columns:1.4fr 1fr 1fr 1.1fr;gap:30px}.footer-brand img{width:190px;filter:brightness(0) invert(1);opacity:.96}.footer-brand p{font-size:13px;max-width:300px;color:#b9cdd4}.footer-col h3{color:#fff;font-size:15px;margin:0 0 12px}.footer-col p,.footer-col li,.footer-col a{font-size:13px}.footer-col ul{list-style:none;padding:0;margin:0}.footer-col li{margin:7px 0}.footer-col a{color:#cbdce2}.footer-col a:hover{color:#fff}.btn-footer{background:transparent;border-color:#5a7a88;color:#fff}.btn-footer:hover{background:rgba(255,255,255,.08);color:#fff}.footer-disclaimer{border-top:1px solid rgba(255,255,255,.12);padding:22px 0;font-size:12px;line-height:1.65;color:#b8cbd2}.footer-bottom{border-top:1px solid rgba(255,255,255,.12);padding:15px 0;font-size:11px;color:#a9c0c8}
.coordinator-fab{position:fixed;right:20px;bottom:20px;z-index:1200;background:var(--op-accent);color:#fff;padding:12px 18px;border-radius:999px;font-weight:800;box-shadow:0 7px 22px rgba(0,0,0,.15)}.coordinator-fab:hover{color:#fff;background:var(--op-accent-dark)}.modal-backdrop{position:fixed;inset:0;background:rgba(14,34,43,.55);display:none;align-items:center;justify-content:center;z-index:1300;padding:18px}.modal-backdrop.open{display:flex}.coordinator-modal{width:min(100%,520px);background:#fff;border-radius:12px;padding:25px;position:relative;box-shadow:0 20px 60px rgba(0,0,0,.25)}.modal-close{position:absolute;right:14px;top:8px;border:0;background:none;font-size:25px;color:#777;cursor:pointer}.coordinator-modal h2{margin:4px 30px 7px 0;color:var(--op-navy)}.coordinator-modal p{font-size:14px;color:var(--op-muted)}.coordinator-form input,.coordinator-form textarea{width:100%;border:1px solid var(--op-line);border-radius:8px;padding:11px;margin:5px 0}.coordinator-form textarea{min-height:85px}.contact-choice{display:grid;grid-template-columns:1fr 1fr;gap:8px;margin-top:10px}.contact-choice a{display:flex;justify-content:center;padding:11px;border-radius:8px;color:#fff;font-weight:800}.wa{background:#25d366}.tg{background:#229ed9}.contact-note{font-size:11px!important;margin:9px 0 0!important}
@media print{.site-header,.footer,.coordinator-fab,.reference-actions,.toc,.side-card{display:none!important}.reference-hero,.content-wrap{padding:0!important}.container{width:100%}.article-content{font-size:12pt}.source-panel{break-inside:avoid}}
@media(max-width:1000px){.header-search{display:none}.header-contact,.language{display:none}.menu-toggle{display:block;margin-left:auto}.main-nav{display:none}.main-nav.open{display:block}.main-menu{display:block}.main-menu li a{border-bottom:1px solid rgba(255,255,255,.1)}.hero-grid,.reference-layout{grid-template-columns:1fr}.card-grid,.footer-grid{grid-template-columns:1fr 1fr}.toc{position:static}.directory-list{grid-template-columns:1fr}.resource-grid{grid-template-columns:1fr}.resource-row{border-right:0;border-bottom:1px solid var(--op-line)}.resource-row:last-child{border-bottom:0}}
@media(max-width:600px){.container{width:min(calc(100% - 24px),var(--op-max))}.header-main{min-height:68px}.brand-logo img{width:160px}.hero{padding:46px 0}.hero h1{letter-spacing:-1.2px}.section{padding:45px 0}.card-grid,.footer-grid{grid-template-columns:1fr}.cta{display:block;padding:28px 22px}.cta .btn{margin-top:18px}.reference-hero{padding:38px 0}.reference-hero h1{font-size:36px}.directory-search{min-width:100%}.az-links{flex-wrap:nowrap;overflow-x:auto;padding-bottom:4px}.az-links a{flex:0 0 35px}.contact-choice{grid-template-columns:1fr}.coordinator-fab{right:12px;bottom:12px;font-size:12px;padding:10px 13px}}

/* =========================================================
   ONCOPOD 2V — REFERENCE UI LAYER
   Consistent editorial UI for directories and individual pages.
   ========================================================= */
:root{
  --op-navy:#102b4e;
  --op-deep:#0b2845;
  --op-green:#0b9b83;
  --op-green-dark:#087a69;
  --op-teal:#0fa9b5;
  --op-pale:#f4fbfa;
  --op-blue-pale:#f4f8fc;
  --op-coral:#f44d62;
  --op-orange:#ff9348;
  --op-text:#1e3150;
  --op-muted:#6d7b8e;
  --op-line:#dfe7eb;
  --op-max:1240px;
  --op-shadow-soft:0 8px 28px rgba(16,43,78,.07);
}
body{font-family:Inter,ui-sans-serif,system-ui,-apple-system,BlinkMacSystemFont,"Segoe UI",Arial,sans-serif;color:var(--op-text);background:#fff;line-height:1.65}
.container{width:min(calc(100% - 40px),var(--op-max))}
.site-header{position:sticky;top:0;background:#fff;border-bottom:1px solid #e6ecef;box-shadow:0 2px 14px rgba(16,43,78,.04)}
.header-main{min-height:82px;gap:28px}
.brand-logo img{width:180px;max-height:60px}
.header-search{max-width:460px}
.search-form{height:42px;border-radius:7px;border-color:#d8e2e8}
.search-form input{font-size:13px;padding:10px 14px}
.search-form button{background:#fff;color:var(--op-navy);border-left:1px solid #d8e2e8;width:46px;padding:0}
.header-contact{background:var(--op-green);border-radius:6px;padding:11px 20px;font-size:13px}
.language{font-weight:700;color:var(--op-navy)}
.main-nav{background:#fff;border-top:1px solid #edf1f3;border-bottom:1px solid #e3eaed}
.main-menu{justify-content:center;gap:0}
.main-menu li a{position:relative;color:var(--op-navy);background:#fff;padding:14px 17px;font-size:12px;font-weight:750}
.main-menu li a:hover{color:var(--op-green-dark);background:#fff}
.main-menu li a:after{content:"";position:absolute;left:14px;right:14px;bottom:0;height:2px;background:transparent}
body.oncopod-drug .main-menu li:nth-child(1) a:after,
body.oncopod-regimen .main-menu li:nth-child(2) a:after,
body.oncopod-side-effect .main-menu li:nth-child(3) a:after{background:var(--op-green)}
body.oncopod-directory-drugs .main-menu li:nth-child(1) a:after,
body.oncopod-directory-treatments .main-menu li:nth-child(2) a:after,
body.oncopod-directory-side-effects .main-menu li:nth-child(3) a:after,
body.oncopod-directory-abbreviations .main-menu li:nth-child(8) a:after{background:var(--op-green)}

/* Individual page hero */
.detail-hero{padding:26px 0 24px;background:#fff}
.breadcrumbs{display:flex;gap:10px;align-items:center;flex-wrap:wrap;color:#758396;font-size:12px;margin:2px 0 18px}
.breadcrumbs a{color:#607287}
.breadcrumbs span:last-child{color:#263b56}
.detail-hero-card{min-height:300px;border:1px solid var(--op-line);border-radius:8px;background:linear-gradient(105deg,#fff 0%,#fff 57%,#fbfdfd 100%);display:grid;grid-template-columns:minmax(0,1.1fr) .9fr;overflow:hidden;box-shadow:0 3px 18px rgba(16,43,78,.035)}
.detail-hero-copy{padding:42px 44px 38px;display:flex;flex-direction:column;justify-content:center}
.detail-hero-copy .eyebrow{font-size:11px;letter-spacing:.12em;color:var(--op-green-dark);font-weight:800;text-transform:uppercase;margin-bottom:9px}
.detail-hero-copy h1{font-size:42px;line-height:1.12;letter-spacing:-1.4px;color:var(--op-navy);margin:0 0 12px;max-width:700px}
.detail-hero-copy p{font-size:16px;line-height:1.65;color:#40526a;max-width:650px;margin:0 0 20px}
.detail-badge{display:inline-flex;width:max-content;border:1px solid #9bd4c8;color:var(--op-green-dark);border-radius:999px;padding:4px 11px;font-size:11px;font-weight:800;margin:0 0 12px}
.detail-actions{display:flex;gap:12px;flex-wrap:wrap}
.detail-hero-art{display:flex;align-items:center;justify-content:center;background:radial-gradient(circle at 60% 50%,#f3fbfa 0,#fff 58%);position:relative;overflow:hidden}
.detail-hero-art:before,.detail-hero-art:after{content:"";position:absolute;border-radius:50%;border:1px solid #eef3f5}
.detail-hero-art:before{width:230px;height:230px;right:5%;top:8%}
.detail-hero-art:after{width:120px;height:120px;left:15%;bottom:5%}
.page-illustration{width:min(78%,340px);color:#0c9a82;position:relative;z-index:1}
.illustration-drug{color:#0877bd}
.illustration-treatment{color:#0b9b83}
.illustration-warning{color:#08a38d;width:min(70%,300px)}

.detail-body{padding:0 0 54px}
.detail-grid{display:grid;grid-template-columns:minmax(0,1fr) 300px;gap:30px;align-items:start}
.detail-main{min-width:0}
.detail-tabs{display:flex;align-items:center;gap:0;border-bottom:1px solid var(--op-line);overflow-x:auto;white-space:nowrap;margin-bottom:22px;scrollbar-width:none}
.detail-tabs::-webkit-scrollbar{display:none}
.detail-tabs a{position:relative;padding:14px 18px;color:#54667b;font-size:12px;font-weight:750}
.detail-tabs a:first-child{padding-left:4px}
.detail-tabs a:hover{color:var(--op-green-dark)}
.detail-tabs a.active{color:var(--op-green-dark)}
.detail-tabs a.active:after{content:"";position:absolute;left:0;right:0;bottom:-1px;height:2px;background:var(--op-green)}
.detail-content{background:#fff;min-width:0}
.detail-content h2{font-size:22px;line-height:1.3;color:var(--op-green-dark);margin:25px 0 8px}
.detail-content h3{font-size:18px;line-height:1.35;color:var(--op-navy);margin:22px 0 7px}
.detail-content p,.detail-content li{font-size:14px;line-height:1.75;color:#40526a}
.detail-content ul,.detail-content ol{padding-left:21px}
.detail-content a{color:var(--op-green-dark);font-weight:650}
.detail-content img{border-radius:8px}
.detail-content table{width:100%;border-collapse:collapse;margin:20px 0;font-size:13px}
.detail-content th,.detail-content td{border:1px solid var(--op-line);padding:11px 12px;text-align:left;vertical-align:top}
.detail-content th{background:#f7fafb;color:var(--op-navy)}
.detail-content blockquote{margin:22px 0;padding:17px 20px;border-left:4px solid var(--op-green);background:var(--op-pale);border-radius:0 8px 8px 0}
.detail-content .wp-caption{max-width:100%}

.reference-sidebar{display:flex;flex-direction:column;gap:16px;position:sticky;top:145px}
.access-card,.question-card,.opinion-card,.journey-card{border:1px solid var(--op-line);border-radius:9px;padding:23px;background:#fff;box-shadow:0 3px 14px rgba(16,43,78,.035)}
.access-card{background:linear-gradient(145deg,#10aeb8,#0a9b83);color:#fff;border-color:transparent;min-height:250px}
.access-icon{font-size:21px;font-weight:850;border:2px solid rgba(255,255,255,.65);border-radius:50%;width:60px;height:60px;display:grid;place-items:center;margin-bottom:18px}
.access-kicker{font-size:11px;font-weight:750;margin-bottom:5px}
.access-card h3{font-size:21px;line-height:1.3;color:#fff;margin:0 0 9px}
.access-card p{font-size:13px;color:rgba(255,255,255,.88);line-height:1.6;margin:0 0 16px}
.btn-light{background:#fff;color:var(--op-green-dark);border:1px solid #fff}
.btn-light:hover{background:#f6ffff;color:var(--op-green-dark)}
.question-card h3,.opinion-card h3{font-size:19px;line-height:1.3;color:var(--op-navy);margin:0 0 10px}
.question-card p,.opinion-card p{font-size:13px;line-height:1.65;color:#64758a;margin:0 0 15px}
.opinion-card{background:#f4fbf8}
.journey-card{border:0;background:linear-gradient(145deg,#f54b63,#ff9a4a);color:#fff;min-height:310px;padding:25px 23px}
.journey-kicker{font-size:19px;font-weight:850;line-height:1.25;display:block;margin-bottom:20px}
.journey-card ul{list-style:none;margin:0 0 20px;padding:0}
.journey-card li{font-size:13px;font-weight:700;margin:12px 0;padding-left:22px;position:relative}
.journey-card li:before{content:"✓";position:absolute;left:0;top:0;width:16px;height:16px;border-radius:50%;background:rgba(255,255,255,.25);display:grid;place-items:center;font-size:10px}
.journey-card p{font-size:13px;color:#fff;margin:0;line-height:1.6}

.detail-help{display:grid;grid-template-columns:55px 1fr auto;align-items:center;gap:16px;border:1px solid var(--op-line);border-radius:9px;padding:17px 20px;margin-top:32px;background:#fff}
.help-icon{width:48px;height:48px;border:2px solid #91d1c5;color:var(--op-green);border-radius:50%;display:grid;place-items:center;font-size:26px}
.detail-help h3{font-size:17px;color:var(--op-navy);margin:0 0 2px}
.detail-help p{font-size:12px;color:var(--op-muted);margin:0}
.source-panel{border:1px solid #cfe3e1;background:#f6fbfa;border-radius:9px;padding:20px 22px;margin-top:28px}
.source-panel h2{font-size:19px;color:var(--op-navy);margin:4px 0 5px}
.source-panel p{font-size:13px;color:#627388}
.source-kicker{font-size:10px;letter-spacing:.12em;color:var(--op-green-dark);font-weight:850}

/* Directory pages closer to the approved visual language */
.reference-hero{padding:25px 0 25px;background:#fff}
.reference-hero .container{position:relative}
.reference-hero h1{font-size:40px;color:var(--op-navy);letter-spacing:-1.2px}
.reference-hero p{max-width:760px;font-size:15px;color:#5c6f83}
.reference-hero:has(+ .content-wrap){}
.directory-toolbar{margin-top:8px}
.directory-list{grid-template-columns:1fr 1fr;gap:0;border:1px solid var(--op-line);border-radius:9px;overflow:hidden;background:#fff}
.directory-item{border:0;border-bottom:1px solid #edf1f3;border-radius:0;padding:13px 38px 13px 16px}
.directory-item:nth-last-child(-n+2){border-bottom:0}
.directory-title{font-size:13px;color:var(--op-green-dark)}
.directory-excerpt{font-size:12px}
.az-group{margin:22px 0 30px}
.az-heading{display:none}
.az-links{margin-bottom:18px}
.az-links a{border-radius:6px}

/* Home remains clean and richer, without becoming colorful */
.hero{background:linear-gradient(180deg,#f4fbfb 0,#fff 100%);padding:66px 0 58px}
.hero h1{font-size:54px;line-height:1.04;color:var(--op-navy);letter-spacing:-2px}
.hero h1 strong,.hero h1 .green{color:var(--op-green)}
.info-card,.resource-row{box-shadow:none;border:1px solid var(--op-line)}
.info-card:hover,.resource-row:hover{box-shadow:var(--op-shadow-soft);transform:translateY(-1px)}
.section-head h2{color:var(--op-navy)}
.cta{background:linear-gradient(105deg,#102d52,#0a6080);border-radius:10px}

.footer{background:#092943;margin-top:40px}
.footer-main{padding:44px 0 30px}
.footer-disclaimer{font-size:11px;line-height:1.6}
.footer-bottom{font-size:11px}

@media(max-width:1000px){
  .header-main{min-height:72px}
  .header-search{display:block;max-width:330px}
  .header-contact,.language{display:none}
  .main-menu{justify-content:flex-start;overflow-x:auto;flex-wrap:nowrap}
  .main-menu li a{font-size:11px;padding:13px 12px}
  .detail-grid{grid-template-columns:1fr}
  .reference-sidebar{position:static;display:grid;grid-template-columns:1fr 1fr}
  .journey-card{grid-column:1/-1}
  .detail-hero-card{grid-template-columns:1fr .7fr}
}
@media(max-width:700px){
  .container{width:min(calc(100% - 24px),var(--op-max))}
  .header-main{min-height:64px}
  .brand-logo img{width:145px}
  .header-search{display:none}
  .main-nav{display:none}
  .main-nav.open{display:block}
  .main-menu{display:block}
  .main-menu li a{border-bottom:1px solid #edf1f3;padding:12px 14px}
  .detail-hero{padding-top:18px}
  .detail-hero-card{display:block}
  .detail-hero-copy{padding:28px 23px 25px}
  .detail-hero-copy h1{font-size:33px;letter-spacing:-.8px}
  .detail-hero-copy p{font-size:14px}
  .detail-hero-art{min-height:190px}
  .page-illustration{width:220px}
  .detail-tabs{margin-bottom:16px}
  .detail-tabs a{padding:12px 14px;font-size:11px}
  .detail-content h2{font-size:20px}
  .detail-content p,.detail-content li{font-size:13px}
  .reference-sidebar{grid-template-columns:1fr}
  .journey-card{grid-column:auto}
  .detail-help{grid-template-columns:45px 1fr}
  .detail-help .btn{grid-column:1/-1;width:100%}
  .directory-list{grid-template-columns:1fr}
  .directory-item:nth-last-child(-n+2){border-bottom:1px solid #edf1f3}
  .directory-item:last-child{border-bottom:0}
  .reference-hero h1{font-size:33px}
}

/* ===== v6.0 reference-page system ===== */
.op-directory-hero,.op-detail-hero{background:#fff;padding:22px 0 28px}
.op-breadcrumb{display:flex;gap:10px;align-items:center;flex-wrap:wrap;color:#738197;font-size:12px;margin:0 0 18px}.op-breadcrumb a{color:#627489}.op-breadcrumb strong{color:#203650;font-weight:700}
.op-directory-hero-card,.op-detail-card{border:1px solid #e2e9ed;border-radius:9px;background:linear-gradient(105deg,#fff 0%,#fff 60%,#fbfdfd 100%);box-shadow:0 4px 20px rgba(16,43,78,.04);min-height:280px;display:grid;grid-template-columns:minmax(0,1.15fr) .85fr;overflow:hidden}
.op-directory-hero-card>div:first-child,.op-detail-copy{padding:42px 44px;display:flex;flex-direction:column;justify-content:center}.op-eyebrow{font-size:10px;letter-spacing:.13em;text-transform:uppercase;color:#008b76;font-weight:850;margin-bottom:10px}.op-directory-hero h1,.op-detail-card h1{font-size:42px;line-height:1.12;letter-spacing:-1.3px;color:#132848;margin:0 0 12px}.op-directory-hero p,.op-detail-card p{font-size:15px;line-height:1.7;color:#53657a;max-width:650px;margin:0 0 18px}.op-hero-icon,.op-detail-art{display:grid;place-items:center;background:radial-gradient(circle at 50% 50%,#f4fbfa 0,#fff 65%);position:relative;color:#009a83}.op-icon-drug{font-size:64px}.op-icon-drug:before{content:'';width:150px;height:95px;border:6px solid currentColor;border-radius:18px;position:absolute;transform:rotate(-28deg)}.op-icon-drug:after{content:'';width:65px;height:105px;border:6px solid currentColor;border-radius:12px;position:absolute;transform:translate(50px,20px)}.op-icon-treatment{font-size:72px}.op-icon-treatment:before{content:'✚';font-size:125px;font-weight:300}.op-side-hero .op-hero-icon{background:#fff}.op-warning-graphic{display:grid;place-items:center;color:#009f87;background:radial-gradient(circle,#f5fcfb,#fff 65%)}.op-warning-graphic:before{content:'';width:155px;height:135px;border:5px solid currentColor;clip-path:polygon(50% 0,100% 100%,0 100%);position:absolute}.op-warning-graphic span{font-size:82px;font-weight:700;z-index:1;margin-top:30px}.op-book-graphic{display:grid;place-items:center;font-size:58px;font-weight:800;color:#0a9b83;background:radial-gradient(circle,#f1fbf8,#fff 65%)}.op-faq-graphic{display:grid;place-items:center;font-size:130px;font-weight:800;color:#0a9b83;background:radial-gradient(circle,#f1fbf8,#fff 65%)}.op-hero-badges{display:flex;gap:10px;flex-wrap:wrap;margin:3px 0 17px}.op-hero-badges span,.op-pill{display:inline-flex;border:1px solid #a8d8cf;border-radius:999px;padding:5px 11px;color:#007e6d;font-size:11px;font-weight:750;background:#fff}.op-hero-actions,.op-detail-actions{display:flex;gap:12px;flex-wrap:wrap}.op-directory-section,.op-detail-section,.op-faq-section{padding:16px 0 58px}.op-two-col{display:grid;grid-template-columns:minmax(0,1fr) 300px;gap:28px;align-items:start}.op-directory-panel{border:1px solid #e2e9ed;border-radius:9px;background:#fff;padding:22px}.op-directory-head{display:flex;justify-content:space-between;gap:20px;align-items:center;margin-bottom:15px}.op-round-icon{width:42px;height:42px;border-radius:50%;display:grid;place-items:center;background:#0b9b83;color:#fff;font-weight:800;margin-bottom:8px}.op-directory-head h2{margin:0 0 4px;color:#162c49;font-size:22px}.op-directory-head p{margin:0;color:#65758a;font-size:13px}.op-search-inline input,.op-faq-search input{height:42px;border:1px solid #dce5e9;border-radius:7px;padding:0 13px;min-width:220px;font:inherit;color:#1b2d45}.op-directory-panel .directory-toolbar{display:none}.op-directory-panel .az-links{margin:18px 0}.op-directory-panel .az-links a{border:1px solid #dfe7ea;background:#fff;color:#203650;padding:7px 10px;font-size:11px}.op-directory-panel .az-links a.active{background:#0b9b83;border-color:#0b9b83;color:#fff}.op-directory-panel .directory-shell{border-top:1px solid #e9eef1}.op-directory-panel .az-group{margin:0}.op-directory-panel .directory-list{display:grid;grid-template-columns:1fr 1fr;border:0}.op-directory-panel .az-heading{display:none}.op-directory-panel .directory-item{border:0;border-bottom:1px solid #edf1f3;border-radius:0;padding:13px 30px 13px 6px;position:relative}.op-directory-panel .directory-item:nth-last-child(-n+2){border-bottom:0}.op-directory-panel .directory-title{font-size:12px;font-weight:750;color:#078873}.op-directory-panel .directory-excerpt{font-size:11px;color:#65758a;margin-top:3px}.op-directory-panel .directory-arrow{right:7px;color:#078873}.op-sidebar{display:flex;flex-direction:column;gap:15px;position:sticky;top:135px}.op-sidebar-card{border:1px solid #e1e8ec;border-radius:9px;background:#fff;padding:22px;box-shadow:0 3px 15px rgba(16,43,78,.035)}.op-sidebar-card h3{font-size:19px;line-height:1.28;color:#152b49;margin:0 0 10px}.op-sidebar-card p{font-size:13px;line-height:1.65;color:#637489;margin:0 0 15px}.op-access{background:#0bb0b4;color:#fff;border-color:transparent}.op-access h3{color:#fff}.op-access p{color:#eaffff}.op-access .op-eyebrow{color:#fff}.op-access-circle{width:55px;height:55px;border:2px solid rgba(255,255,255,.75);border-radius:50%;display:grid;place-items:center;font-weight:800;margin-bottom:15px}.op-white,.btn-white{background:#fff;color:#008676;border-color:#fff}.op-opinion{background:#f5fbf9}.op-journey{background:linear-gradient(145deg,#f24c63,#ff9b48);color:#fff;min-height:300px}.op-journey h3,.op-journey p{color:#fff}.op-journey ul{padding:0;margin:0 0 16px;list-style:none}.op-journey li{font-size:12px;font-weight:700;margin:12px 0;padding-left:20px;position:relative}.op-journey li:before{content:'✓';position:absolute;left:0;top:0}.op-quick-links{list-style:none;padding:0;margin:0}.op-quick-links li{border-top:1px solid #edf1f3}.op-quick-links a{display:flex;justify-content:space-between;padding:12px 0;color:#31455e;font-size:12px}.op-quick-links b{color:#0a9b83}.op-support-strip{display:grid;grid-template-columns:50px 1fr auto;gap:14px;align-items:center;border:1px solid #dfe7ea;border-radius:9px;padding:15px 18px;margin-top:18px;background:#fff}.op-support-icon{width:46px;height:46px;border:2px solid #94d1c6;border-radius:50%;display:grid;place-items:center;color:#008f7b}.op-support-strip strong{display:block;color:#172d49;font-size:16px;margin-bottom:2px}.op-support-strip span{display:block;color:#65758a;font-size:12px}.op-feedback{display:flex;align-items:center;gap:12px;border:1px solid #e1e8ec;border-radius:9px;padding:18px;margin-top:18px}.op-feedback strong{margin-right:auto;color:#1b304b}.op-faq-main{min-width:0}.op-faq-search{margin-bottom:16px}.op-faq-search input{width:100%;min-width:0}.op-faq-card{border:1px solid #e1e8ec;border-radius:8px;margin-bottom:10px;background:#fff;overflow:hidden}.op-faq-question{width:100%;border:0;background:#fff;padding:18px 20px;display:flex;justify-content:space-between;text-align:left;color:#172d49;font-size:14px;font-weight:750;cursor:pointer}.op-faq-question b{font-size:20px;color:#0a9b83}.op-faq-answer{display:none;padding:0 20px 18px;color:#5e7084;font-size:13px;line-height:1.7}.op-faq-card.open .op-faq-answer{display:block}.op-empty-card{padding:35px;border:1px solid #e1e8ec;border-radius:9px}.op-detail-card{min-height:300px}.op-detail-copy h1{max-width:700px}.op-detail-art{min-height:280px}.op-detail-art .page-illustration{width:300px;color:#0b9b83}.op-detail-drug .op-detail-art .page-illustration{color:#0b63b9}.op-detail-side-effects .op-detail-art .page-illustration{color:#0a9f8b}.op-detail-tabs{display:flex;gap:0;border-bottom:1px solid #dfe7ea;overflow:auto;white-space:nowrap;margin-bottom:22px}.op-detail-tabs a{padding:15px 18px;color:#53667c;font-size:12px;font-weight:750;position:relative}.op-detail-tabs a:first-child{padding-left:4px}.op-detail-tabs a.active{color:#008a76}.op-detail-tabs a.active:after{content:'';position:absolute;left:0;right:0;bottom:-1px;height:2px;background:#0a9b83}.op-rich-content{font-size:14px;color:#40536a;line-height:1.75}.op-rich-content h2{font-size:21px;color:#078873;margin:25px 0 8px}.op-rich-content h3{font-size:17px;color:#162d4a;margin:22px 0 7px}.op-rich-content p,.op-rich-content li{font-size:13px;line-height:1.75}.op-rich-content a{color:#008b76;font-weight:700}.op-intro-panel{padding-bottom:4px}.op-common-effects{margin-top:20px}.op-effect-grid{display:grid;grid-template-columns:repeat(4,1fr);gap:10px}.op-effect-grid span{border:1px solid #e1e8ec;border-radius:7px;padding:15px 8px;text-align:center;font-size:11px;color:#213651;background:#fff}.op-source-panel{border:1px solid #cfe4df;background:#f5fbf9;border-radius:9px;padding:20px;margin-top:28px}.op-source-panel h2{font-size:19px;color:#162d4a;margin:4px 0}.op-source-panel p{font-size:12px;color:#637489}.op-detail-main .op-support-strip{margin-top:28px}
@media(max-width:900px){.op-two-col{grid-template-columns:1fr}.op-sidebar{position:static;display:grid;grid-template-columns:1fr 1fr}.op-journey{grid-column:1/-1}.op-directory-panel .directory-list{grid-template-columns:1fr}.op-directory-panel .directory-item:nth-last-child(-n+2){border-bottom:1px solid #edf1f3}.op-directory-panel .directory-item:last-child{border-bottom:0}.op-detail-card,.op-directory-hero-card{grid-template-columns:1fr}.op-detail-art,.op-hero-icon,.op-warning-graphic,.op-book-graphic,.op-faq-graphic{min-height:190px}.op-effect-grid{grid-template-columns:repeat(2,1fr)}}
@media(max-width:650px){.op-directory-hero h1,.op-detail-card h1{font-size:32px}.op-directory-hero-card>div:first-child,.op-detail-copy{padding:28px 22px}.op-directory-head{display:block}.op-search-inline{margin-top:15px}.op-search-inline input{width:100%;min-width:0}.op-sidebar{grid-template-columns:1fr}.op-journey{grid-column:auto}.op-support-strip{grid-template-columns:44px 1fr}.op-support-strip .btn{grid-column:1/-1;width:100%}.op-feedback{display:grid}.op-feedback strong{margin:0}.op-detail-tabs a{padding:12px 13px;font-size:11px}}
/* ===== Approved home composition ===== */
.op-home-hero{background:linear-gradient(180deg,#f5fbfb 0,#fff 100%);padding:48px 0 35px}.op-home-hero-grid{display:grid;grid-template-columns:1.08fr .92fr;gap:42px;align-items:center}.op-home-hero h1{font-size:52px;line-height:1.05;letter-spacing:-2px;color:#132848;margin:10px 0 18px}.op-home-hero h1 span{color:#079c88}.op-home-hero p{font-size:16px;line-height:1.7;color:#586a7e;max-width:650px}.op-home-actions{display:flex;gap:12px;flex-wrap:wrap;margin-top:22px}.op-home-actions b{margin-left:8px}.op-home-hero-card{border:1px solid #dce7e8;border-radius:12px;background:linear-gradient(145deg,#fff,#f1fbfa);padding:34px;box-shadow:0 5px 22px rgba(15,55,74,.05);text-align:center}.op-home-hero-card-title{font-size:11px;letter-spacing:.15em;color:#079a85;font-weight:850}.op-home-hero-card h2{font-size:27px;line-height:1.25;color:#172d4b;margin:8px 0 12px}.op-home-hero-card p{font-size:13px;margin:0 auto 22px}.op-proof-row{display:grid;grid-template-columns:repeat(4,1fr);gap:10px;border-top:1px solid #dbe8e6;padding-top:17px}.op-proof-row span{color:#079a85;font-size:22px;font-weight:800}.op-proof-row small{display:block;font-size:9px;line-height:1.35;color:#5f7183;font-weight:650}.op-home-tools{background:#fff;border-bottom:1px solid #e4eaed}.op-tool-grid{display:grid;grid-template-columns:repeat(6,1fr);border:1px solid #e1e8eb;border-top:0;border-radius:0 0 10px 10px;overflow:hidden}.op-tool-grid a{padding:18px 10px;text-align:center;border-right:1px solid #e1e8eb;color:#1a304b}.op-tool-grid a:last-child{border-right:0}.op-tool-grid b{display:block;color:#079a85;font-size:25px;line-height:1;margin-bottom:8px}.op-tool-grid strong{display:block;font-size:12px}.op-tool-grid span{display:block;font-size:10px;line-height:1.4;color:#667789;margin-top:4px}.op-home-content{padding:30px 0 20px}.op-home-content-grid{display:grid;grid-template-columns:1fr 1fr 285px;gap:18px}.op-home-section-head{display:flex;justify-content:space-between;align-items:end;gap:10px;margin-bottom:10px}.op-home-section-head h2{font-size:20px;color:#162d4a;margin:0}.op-home-section-head p{font-size:11px;color:#687a8c;margin:3px 0 0}.op-home-section-head>a{font-size:10px;color:#008b76;font-weight:800;white-space:nowrap}.op-list-card{border:1px solid #e1e8ec;border-radius:9px;background:#fff;overflow:hidden}.op-list-card a{display:grid;grid-template-columns:28px 1fr 15px;gap:9px;align-items:center;padding:12px 12px;border-bottom:1px solid #edf1f3;color:#1c304a}.op-list-card a:last-child{border-bottom:0}.op-list-card a:hover{background:#f7fbfa}.op-list-icon{width:26px;height:26px;border-radius:7px;background:#eef8f5;color:#078b77;display:grid;place-items:center;font-size:9px;font-weight:850}.op-list-card strong{display:block;font-size:11px}.op-list-card small{display:block;font-size:9px;color:#6a7b8b;line-height:1.35;margin-top:2px}.op-list-card>b{color:#079a85}.op-inline-link{display:inline-block;font-size:11px;font-weight:800;color:#008b76;margin:10px 0}.op-home-aside{display:flex;flex-direction:column;gap:12px}.op-home-access{background:#09a9b0;color:#fff;border-radius:9px;padding:20px;min-height:225px}.op-home-access h3{font-size:20px;line-height:1.25;margin:8px 0}.op-home-access p{font-size:11px;line-height:1.55;color:#e9ffff;margin:0 0 12px}.op-home-question{border:1px solid #e1e8ec;border-radius:9px;padding:20px}.op-home-question h3{font-size:17px;line-height:1.25;color:#172d4a;margin:0 0 8px}.op-home-question p{font-size:11px;color:#64758a}.op-home-support{padding:0 0 28px}.op-home-support .container{border:1px solid #dfe8eb;border-radius:9px;background:#f4faf9;padding:15px 20px;display:flex;justify-content:space-between;align-items:center;gap:20px}.op-home-support .container>div{display:flex;gap:12px;align-items:center}.op-home-support b{font-size:28px;color:#008d79}.op-home-support h3{margin:0;color:#172d49;font-size:16px}.op-home-support p{margin:2px 0 0;font-size:11px;color:#66798a}.op-home-insights{padding:25px 0 32px}.op-insight-grid{display:grid;grid-template-columns:repeat(4,1fr);gap:16px}.op-insight-grid article{border:1px solid #e1e8ec;border-radius:9px;overflow:hidden;background:#fff}.op-insight-img{height:115px;background:linear-gradient(135deg,#dff3f2,#f4f8f8)}.op-img-1{background:linear-gradient(135deg,#dff1f3,#c6e8eb)}.op-img-2{background:linear-gradient(135deg,#eef3ee,#d7e7df)}.op-img-3{background:linear-gradient(135deg,#f4e5df,#e8d3c6)}.op-img-4{background:linear-gradient(135deg,#dbe8f2,#b9d1e6)}.op-insight-grid article small{display:block;margin:10px 12px 4px;color:#078b77;font-size:9px;font-weight:800}.op-insight-grid h3{font-size:14px;line-height:1.35;color:#172d49;margin:0 12px 5px}.op-insight-grid p{font-size:10px;color:#68798a;line-height:1.45;margin:0 12px 14px}.op-home-types{padding:0 0 28px}.op-type-grid{display:grid;grid-template-columns:repeat(6,1fr);gap:10px}.op-type-grid span{border:1px solid #e1e8ec;border-radius:8px;padding:18px 8px;text-align:center;color:#19314d;font-size:11px;font-weight:750;background:#fff}.op-home-cta{padding:12px 0 35px}.op-home-cta .container{background:#092b4b;border-radius:10px;color:#fff;padding:23px 28px;display:grid;grid-template-columns:65px 1fr auto;gap:18px;align-items:center}.op-home-cta-icon{width:55px;height:55px;border-radius:50%;border:2px solid #42d3c0;display:grid;place-items:center;font-size:28px;color:#42d3c0}.op-home-cta h2{margin:0 0 5px;font-size:20px}.op-home-cta p{margin:0;color:#d5e3ea;font-size:11px;line-height:1.55}.op-home-cta .btn{background:#fff;color:#132d4b}
@media(max-width:900px){.op-home-hero-grid{grid-template-columns:1fr}.op-tool-grid{grid-template-columns:repeat(3,1fr)}.op-tool-grid a:nth-child(3){border-right:0}.op-tool-grid a:nth-child(-n+3){border-bottom:1px solid #e1e8eb}.op-home-content-grid{grid-template-columns:1fr 1fr}.op-home-aside{grid-column:1/-1;display:grid;grid-template-columns:1fr 1fr}.op-insight-grid{grid-template-columns:1fr 1fr}.op-type-grid{grid-template-columns:repeat(3,1fr)}}
@media(max-width:650px){.op-home-hero h1{font-size:37px}.op-proof-row{grid-template-columns:repeat(2,1fr)}.op-tool-grid{grid-template-columns:repeat(2,1fr)}.op-tool-grid a:nth-child(3){border-right:1px solid #e1e8eb}.op-tool-grid a:nth-child(2n){border-right:0}.op-tool-grid a:nth-child(n+3){border-bottom:0}.op-home-content-grid{grid-template-columns:1fr}.op-home-aside{grid-column:auto;grid-template-columns:1fr}.op-insight-grid{grid-template-columns:1fr}.op-type-grid{grid-template-columns:repeat(2,1fr)}.op-home-support .container{display:block}.op-home-support .container>div{margin-bottom:12px}.op-home-cta .container{grid-template-columns:1fr}.op-home-cta .btn{width:100%}}
/* Global header — approved white navigation treatment */
.site-header{position:relative;box-shadow:none}.main-nav{background:#fff;border-top:1px solid #edf1f3;border-bottom:1px solid #e1e8ec}.main-menu{justify-content:center}.main-menu li a{color:#162c49;font-size:12px;padding:12px 15px;position:relative}.main-menu li a:hover{background:#f6faf9;color:#008b76}.main-menu li a:after{content:'';position:absolute;left:15px;right:15px;bottom:-1px;height:2px;background:transparent}.main-menu li a:hover:after{background:#8dcfc4}.header-contact{border-radius:6px;padding:10px 18px}.header-search .search-form{border-radius:7px}.language{display:none}.coordinator-fab{background:#0aa98f}.op-page-drug-info .main-menu li:nth-child(1) a:after,.op-page-treatment-acronyms .main-menu li:nth-child(2) a:after,.op-page-side-effects .main-menu li:nth-child(3) a:after,.op-page-abbreviations .main-menu li:nth-child(8) a:after{background:#0a9b83}
@media(max-width:700px){.main-nav{display:none}.main-nav.open{display:block}.main-menu{display:block}.main-menu li a{padding:12px 15px}.main-menu li a:after{left:0;right:auto;width:3px;height:auto;top:0;bottom:0}.header-main{min-height:68px}.brand-logo img{width:165px}.menu-toggle{display:block}.header-contact{display:none}}


/* =========================================================
   v6.1 FINAL VISUAL CONSISTENCY
   White editorial surfaces; identical logo in header/footer.
   ========================================================= */
:root{
  --op-surface:#ffffff;
  --op-page:#ffffff;
  --op-border:#dfe7ea;
}
body{background:#fff}
/* All content cards/boxes stay white; color is reserved for accents, icons and buttons. */
.info-card,.resource-row,.hero-reference,.op-directory-hero-card,.op-detail-card,
.op-directory-panel,.op-sidebar-card,.op-support-strip,.op-feedback,.op-faq-card,
.op-empty-card,.op-source-panel,.op-intro-panel,.op-common-effects,.op-rich-content,
.op-detail-main,.op-acronym-sidebar,.op-sidebar,.reference-layout aside .side-card,
.search-result,.toc,.side-card,.directory-shell,.directory-list,
.op-home-card,.op-insight-grid article,.op-treatment-card,.op-condition-card,
.op-tool-card,.op-quick-card,.op-content-card{
  background:#fff !important;
}
/* Keep page and hero backgrounds clean and white. */
.hero,.section,.section-alt,.op-directory-hero,.op-detail-hero,
.op-directory-section,.op-detail-section,.op-faq-section,.op-home-insights,
.reference-hero,.content-wrap{background:#fff}
/* Same exact logo asset and treatment in header and footer. */
.site-header .brand-logo img,.footer-brand .brand-logo img,.footer-brand img{
  width:190px;height:auto;max-height:58px;filter:none !important;opacity:1 !important;
}
.footer-brand .brand-logo{display:inline-flex}
.footer-brand .brand-logo img{width:190px}
/* Footer is white, with restrained editorial dividers. */
.footer{background:#fff !important;color:#526574;border-top:1px solid var(--op-line);margin-top:50px}
.footer-main{background:#fff;padding:46px 0 30px}
.footer-grid{background:#fff}
.footer-brand p{color:#647681}
.footer-col h3{color:var(--op-navy)}
.footer-col p,.footer-col li{color:#647681}
.footer-col a{color:#526574}
.footer-col a:hover{color:var(--op-accent-dark)}
.btn-footer{background:#fff;color:var(--op-accent-dark);border-color:#9fcfc7}
.btn-footer:hover{background:#f5fbfa;color:var(--op-accent-dark)}
.footer-disclaimer{background:#fff;border-top:1px solid var(--op-line);color:#647681}
.footer-bottom{background:#fff;border-top:1px solid var(--op-line);color:#74838d}
/* Do not let the older dark CTA/card rules recolor boxed components. */
.info-card:hover,.resource-row:hover{background:#fff !important}
.op-directory-hero-card,.op-detail-card{background:#fff !important}
/* Intentional full-width CTA bands may retain their accent treatment, but not boxed cards. */
.cta{color:#fff}
/* Mobile: logo remains the same asset and white footer stays white. */
@media(max-width:600px){
  .site-header .brand-logo img,.footer-brand .brand-logo img,.footer-brand img{width:160px;max-height:52px}
}

/* v6.2: final visual corrections */
.footer,.footer-main,.footer-grid,.footer-disclaimer,.footer-bottom{background:#fff !important;color:#526574 !important;}
.footer{border-top:1px solid #e2e9ec !important;}
.footer-disclaimer,.footer-bottom{border-color:#e2e9ec !important;}
.footer-brand img,.footer-brand .brand-logo img{filter:none !important;opacity:1 !important;}
.footer-brand .brand-logo img,.site-header .brand-logo img{width:190px;height:auto;}
.footer-col h3{color:#132848 !important;}
.footer-col p,.footer-col li,.footer-col a{color:#5e7080 !important;}
.footer-col a:hover{color:#008b76 !important;}
.btn-footer{background:#fff !important;color:#008b76 !important;border:1px solid #9fcfc7 !important;}
.footer-disclaimer,.footer-bottom{color:#667785 !important;}
.az-links a{order:0;}
.az-links a[data-letter="all"]{order:99;}

/* =========================================================
   v6.3 FINAL CONTENT + SURFACE CORRECTIONS
   ========================================================= */
/* Every editorial box stays white. Accent is reserved for borders, icons and buttons. */
.op-home-cta .container,
.op-home-access,
.op-home-question,
.op-sidebar-card,
.reference-sidebar .access-card,
.reference-sidebar .question-card,
.reference-sidebar .opinion-card,
.reference-sidebar .journey-card,
.op-journey,
.op-treatment-card,
.op-medicine-card,
.op-regimen-medicines,
.op-empty-content{background:#fff !important;color:var(--op-navy) !important;border:1px solid var(--op-line) !important;}
.op-home-cta .container{color:var(--op-navy) !important;box-shadow:none !important;}
.op-home-cta h2,.op-home-cta p{color:var(--op-navy) !important;}
.op-home-cta p{color:#64758a !important;}
.op-home-cta-icon{color:#0a9b83 !important;border-color:#7acbbd !important;}
.op-home-cta .btn{background:#0a9b83 !important;color:#fff !important;border-color:#0a9b83 !important;}
.op-home-access h3,.op-home-access p,.op-sidebar-card h3,.op-sidebar-card p,.journey-card,.journey-card p{color:var(--op-navy) !important;}
.op-home-access .btn,.op-sidebar-card.op-access .btn,.access-card .btn{background:#0a9b83 !important;color:#fff !important;border-color:#0a9b83 !important;}
.op-sidebar-card.op-access .op-eyebrow,.access-card .access-kicker{color:#078b77 !important;}
.op-sidebar-card.op-access .op-access-circle,.access-card .access-icon{color:#078b77 !important;border-color:#8bcfc4 !important;background:#f4fbfa !important;}
.op-journey .journey-kicker,.journey-card .journey-kicker{color:#078b77 !important;}
.op-journey li,.journey-card li{color:#53667a !important;}
/* Footer is a white editorial footer on every template. */
footer.footer,footer.footer .footer-main,footer.footer .footer-grid,footer.footer .footer-disclaimer,footer.footer .footer-bottom{background:#fff !important;background-color:#fff !important;}
footer.footer{color:#526574 !important;border-top:1px solid #e2e9ec !important;}
.footer-brand .brand-logo,.footer-brand .brand-logo img{background:transparent !important;filter:none !important;opacity:1 !important;mix-blend-mode:normal !important;}
.footer-brand .brand-logo img,.site-header .brand-logo img{width:190px !important;height:auto !important;max-height:none !important;}
.footer-col h3{color:#132848 !important}.footer-col p,.footer-col li,.footer-col a{color:#5e7080 !important}.footer-col a:hover{color:#008b76 !important}
.btn-footer{background:#fff !important;color:#008b76 !important;border:1px solid #9fcfc7 !important;}
/* Directory: A is the opening state; ALL is always last. */
.az-links{display:flex;align-items:center;gap:6px;}
.az-links a{order:0 !important;}
.az-links a[data-letter="all"]{order:100 !important;}
/* Treatment/regimen individual page. */
.op-regimen-medicines{margin:28px 0;padding:22px;border-radius:9px;}
.op-section-kicker{font-size:10px;letter-spacing:.13em;text-transform:uppercase;color:#008b76;font-weight:850;margin-bottom:6px;}
.op-regimen-medicines h2{margin:0 0 6px !important;color:#162d4a !important;}
.op-section-intro{margin:0 0 16px !important;color:#63758a !important;}
.op-medicine-grid{display:grid;grid-template-columns:repeat(2,minmax(0,1fr));gap:10px;}
.op-medicine-card{display:grid;grid-template-columns:42px 1fr;gap:12px;padding:15px;border-radius:8px;}
.op-medicine-icon{width:38px;height:38px;border-radius:8px;background:#eff9f7;color:#078b77;display:grid;place-items:center;font-size:10px;font-weight:850;}
.op-medicine-card h3{margin:0 0 4px;font-size:14px;color:#162d4a;}
.op-medicine-card h3 a{color:#008b76;}
.op-medicine-card p{margin:0 !important;font-size:12px !important;line-height:1.55 !important;color:#64758a !important;}
.op-empty-content{padding:24px;border-radius:9px;margin-top:24px;}
.op-empty-content h2{margin-top:0 !important;}
@media(max-width:700px){.op-medicine-grid{grid-template-columns:1fr}.footer-brand .brand-logo img,.site-header .brand-logo img{width:160px !important;}}

/* ===== v6.4 navigation and treatment taxonomy ===== */
.main-menu li a{font-size:12px;padding-left:12px;padding-right:12px}
.main-menu li a.active,
.main-menu li a[aria-current="page"]{color:#008b76 !important}
.op-page-cancer-treatments .main-menu li:nth-child(1) a:after,
.op-page-drug-info .main-menu li:nth-child(2) a:after,
.op-page-treatment-acronyms .main-menu li:nth-child(3) a:after,
.op-page-side-effects .main-menu li:nth-child(4) a:after,
.op-page-faqs .main-menu li:nth-child(5) a:after,
.op-page-abbreviations .main-menu li:nth-child(9) a:after{background:#0a9b83 !important}
.az-links a[data-letter="all"]{order:100 !important}
.az-links a.active[data-letter="all"]{background:#fff !important;border-color:var(--op-line) !important;color:var(--op-accent-dark) !important}
.az-links a.active:not([data-letter="all"]){background:var(--op-accent) !important;border-color:var(--op-accent) !important;color:#fff !important}

/* Cancer treatment type directory */
.op-cancer-treatment-hero{background:#fff !important}
.op-treatment-types-section{padding:38px 0 45px;background:#fff}
.op-treatment-types-intro{margin-bottom:22px}
.op-treatment-types-intro h2{font-size:30px;color:#162d4a;margin:5px 0 7px}
.op-treatment-types-intro p{max-width:800px;color:#65758a;line-height:1.7;margin:0}
.op-treatment-type-grid{display:grid;grid-template-columns:repeat(3,1fr);gap:16px}
.op-treatment-type-card{display:block;background:#fff;border:1px solid #e1e8ec;border-radius:10px;padding:22px;color:#40536a;box-shadow:0 4px 16px rgba(15,55,74,.035);transition:.2s}
.op-treatment-type-card:hover{border-color:#a8d1ca;box-shadow:0 7px 22px rgba(15,55,74,.07);transform:translateY(-1px)}
.op-treatment-type-card h3{color:#162d4a;font-size:18px;margin:10px 0 7px}
.op-treatment-type-card p{font-size:13px;line-height:1.7;margin:0 0 13px}
.op-treatment-type-card b{font-size:12px;color:#008b76}
.op-type-icon{width:42px;height:42px;border:1px solid #b9ddd7;border-radius:10px;display:grid;place-items:center;color:#078b77;font-weight:850;font-size:13px;background:#fff}
.op-treatment-note{margin-top:20px;padding:18px 20px;border:1px solid #dfe8eb;border-radius:9px;background:#fff;color:#637489;font-size:12px;line-height:1.65}
.op-treatment-note strong{color:#162d4a}
.op-treatment-type-graphic{width:260px;height:220px;display:flex;align-items:center;justify-content:center;gap:14px;color:#0a9b83;font-size:58px;opacity:.9}
.op-treatment-type-graphic span:nth-child(2){font-size:90px;color:#d6ece8}.op-treatment-type-graphic span:nth-child(3){font-size:72px;color:#9fd3cd}
.footer-brand-note{margin-top:8px !important}.footer-brand-note a{color:#008b76 !important;font-weight:700}.footer-link-button{background:none;border:0;padding:0;color:#5e7080;font:inherit;cursor:pointer}.footer-link-button:hover{color:#008b76}.footer-help{margin-top:12px}.footer-bottom .container{display:flex;justify-content:space-between;gap:20px}.footer-bottom a{color:#008b76;font-weight:700}
@media(max-width:900px){.op-treatment-type-grid{grid-template-columns:1fr 1fr}.op-treatment-type-graphic{margin:auto}.footer-bottom .container{display:block}.footer-bottom .container span{display:block;margin-top:4px}}
@media(max-width:650px){.op-treatment-type-grid{grid-template-columns:1fr}.op-treatment-type-graphic{width:100%;height:150px}.op-treatment-type-graphic span{font-size:42px!important}.footer-bottom .container{font-size:10px}}

/* v6.4.1 production footer — white editorial surface */
.footer{background:#fff !important;color:#263944 !important;margin-top:50px;border-top:1px solid #e2eaed;}
.footer-main{background:#fff !important;padding:58px 0 46px;}
.footer-grid-final{grid-template-columns:1.25fr .9fr 1.45fr .8fr;gap:44px;align-items:start;}
.footer-brand img{filter:none !important;width:190px !important;height:auto !important;}
.footer-brand p{color:#435767 !important;font-size:15px;line-height:1.8;max-width:350px;}
.footer-brand-note{margin-top:28px !important;}
.footer-brand-note a,.footer-guidance strong{color:#008f83 !important;}
.footer-col h3{color:#132848 !important;font-size:22px !important;margin:0 0 22px !important;position:relative;padding-bottom:12px;}
.footer-col h3:after{content:"";position:absolute;left:0;bottom:0;width:44px;height:2px;background:#0a9b83;}
.footer-col a,.footer-col p,.footer-col li{color:#536779 !important;}
.footer-col a:hover{color:#008f83 !important;}
.footer-col li{margin:13px 0 !important;font-size:15px !important;}
.footer-guidance .footer-contact-item{display:flex;gap:14px;align-items:flex-start;margin:18px 0;}
.footer-contact-icon{width:48px;height:48px;border-radius:50%;border:1px solid #c7e3e5;background:#f4fbfb;color:#008f83;display:grid;place-items:center;font-weight:800;font-size:20px;flex:0 0 48px;}
.footer-guidance strong{font-size:17px;display:block;margin-bottom:4px;}
.footer-guidance p{margin:0 !important;font-size:14px !important;line-height:1.5;}
.footer-social-links{display:flex;gap:12px;flex-wrap:wrap;margin-top:48px;}
.footer-social-links a{width:46px;height:46px;border-radius:50%;display:grid;place-items:center;background:#123b67 !important;color:#fff !important;font-weight:800;font-size:17px;text-decoration:none;}
.footer-social-links a:hover{background:#008f83 !important;color:#fff !important;}
.footer-disclaimer{background:#f2f9fa !important;border-top:1px solid #e1ecee !important;padding:30px 0 !important;color:#526777 !important;}
.footer-disclaimer-inner{display:flex;gap:24px;align-items:center;font-size:14px;line-height:1.75;}
.footer-disclaimer-inner strong{color:#008f83;}
.footer-disclaimer-icon{width:70px;height:70px;border-radius:50%;border:1px solid #c5e1e4;background:#e8f5f6;color:#087d78;display:grid;place-items:center;font-size:28px;font-weight:800;flex:0 0 70px;}
.footer-bottom{background:#fff !important;border-top:1px solid #e1e7ea !important;padding:22px 0 !important;color:#526777 !important;}
.footer-bottom-inner{display:flex;align-items:center;gap:28px;font-size:14px;position:relative;}
.footer-bottom-inner span:nth-child(2){flex:1;text-align:center;}
.footer-ribbon{color:#1aa59b;font-size:30px;margin-left:auto;}
.btn-footer{background:#fff !important;color:#008b83 !important;border-color:#9fcfc7 !important;}
@media(max-width:900px){.footer-grid-final{grid-template-columns:1fr 1fr;}.footer-bottom-inner{flex-wrap:wrap;}.footer-bottom-inner span:nth-child(2){text-align:left;flex:auto;}}
@media(max-width:600px){.footer-grid-final{grid-template-columns:1fr;}.footer-main{padding:38px 0;}.footer-disclaimer-inner{align-items:flex-start;}.footer-bottom-inner{display:block;}.footer-bottom-inner span{display:block;margin:7px 0;}.footer-ribbon{display:none !important;}}