What is ALOXI?
ALOXI is used in adults to help prevent the nausea and vomiting that happens:
- right away or later with certain anti-cancer medicines (chemotherapy)
- up to 24 hours while recovering from anesthesia after surgery
ALOXI is used in children 1 month old to less than 17 years of age to help prevent the nausea and vomiting that happens right away with certain anti-cancer medicines (chemotherapy).
- It is not known if ALOXI is safe and effective in children less than 1 month old to help prevent nausea and vomiting after chemotherapy.
- It is not known if ALOXI is safe and effective in children for the prevention of nausea and vomiting while recovering from anesthesia after surgery.
What is the most important information I should know about ALOXI?
ALOXI can cause serious side effects. These serious side effects include:
- ALOXI can cause allergic reactions that can sometimes be serious. Tell your doctor or nurse right away if you have any of the following symptoms of a serious allergic reaction with ALOXI:
- hives
- breathing trouble
- chest pain
- swollen face
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The most common side effects of ALOXI in adults are headache and constipation.
These are not all the possible side effects from ALOXI.
How will I receive ALOXI?
- ALOXI will be given to you in your vein by intravenous (I.V.) injection.
- ALOXI is usually given about 30 minutes before you receive your anti-cancer medicine (chemotherapy) or right before anesthesia for surgery.
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Important Safety Information
Do not receive ALOXI if you are allergic to palonosetron hydrochloride or any of the ingredients in ALOXI
Tell your doctor or nurse right away if you have any of the following symptoms with ALOXI:
- Hives
- Swollen face
- Breathing trouble
- Chest pain
Ask your healthcare provider if you do not know.
What should I tell my healthcare provider before taking ALOXI?
Before receiving ALOXI, tell your doctor about all of your medical conditions, including if you:
- have had an allergic reaction to another medicine for nausea or vomiting
- are pregnant or plan to become pregnant. It is not known if ALOXI will harm your unborn baby.
- are breastfeeding or plan to breastfeed. It is not known if ALOXI passes into your breast milk. You and your doctor should decide if you will receive ALOXI if you breastfeed.
Tell your doctor about all of the medicines you take, including prescription and over-the-counter medicines, vitamins and herbal supplements.
General information about ALOXI
Medicines are sometimes prescribed for purposes other than those listed in a Patient Information leaflet. You can ask your doctor or pharmacist for information about ALOXI that is written for health professionals.
What are the ingredients in ALOXI?
Active ingredient: Palonosetron Hydrochloride
Other ingredient: Mannitol, disodium edetate, and citrate buffer in water